高辛亚

博士 博士后 医师

EMAIL:SURGEONG@163.COM

个人简介

高辛亚，博士毕业于中山大学附属第一医院，师从张弩院长，后留院进行博士后工作，顺利出站。 从事环状RNA翻译蛋白对恶性肿瘤发生发展的影响的机制研究。近五年以第一作者在本领域内发表相关论文4篇。 其中IF>20两篇，IF>10一篇（Nature cell biology，IF=28.824,第一作者第一， Journal of the national cancer institute, IF=13.506, 共一第二，Molecular cancer, IF=44.401，共一第二）。申请人已获得国自然青年项目资助，同时作为十四五科技部国家重点研发计划青年科学家项目项目骨干，获资100万。

研究领域

基于高通量翻译组的乳腺癌靶向治疗

科研成果

主要科研成果（#共同第一作者, *通讯作者）如下：

1. Gao Xinya#,Xia Xin,Li Fanying et al. Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR-STAT3 signalling.[J] . Nat Cell Biol, 2021, 23: 278-291.


2. Li Jie,Gao Xinya#,Zhang Zhanqiang et al. plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes.[J] . Mol Cancer, 2021, 20: 138.


3. Gao Xinya#,Lai Yuanhui,Zhang Zhanqiang et al. Long Non-coding RNA RP11-480I12.5 Promotes the Proliferation, Migration, and Invasion of Breast Cancer Cells Through the miR-490-3p-AURKA-Wnt/β-Catenin Axis.[J] .Front Oncol, 2020, 10: 948.


4. Yang Yibing,Gao Xinya#,Zhang Maolei et al. Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis.[J] . J Natl Cancer Inst, 2018, 110: undefined.

代表性论著：

1. Gao Xinya^#, Xia Xin^#,Li Fanying et al. Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR-STAT3 signalling.[J] . Nat Cell Biol, 2021, 23: 278-291.

2. Li Jie^#,Gao Xinya^#,Zhang Zhanqiang et al. plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes.[J] . Mol Cancer, 2021, 20: 138.

3. Gao Xinya^#,Lai Yuanhui^#,Zhang Zhanqiang et al. Long Non-coding RNA RP11-480I12.5 Promotes the Proliferation, Migration, and Invasion of Breast Cancer Cells Through the miR-490-3p-AURKA-Wnt/β-Catenin Axis.[J] .Front Oncol, 2020, 10: 948.

4. Yang Yibing^#,Gao Xinya^#,Zhang Maolei et al. Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis.[J] . J Natl Cancer Inst, 2018, 110: undefined.