王明

博士 研究主管

EMAIL: WANGM08@YEAH.NET

个人简介

王明，博士毕业于中国科学院生物物理研究所， 2023-至今工作于广州市妇女儿童医疗中心优生围产研究所研究主管岗位，参与国家自然科学基金项目1项等。

研究领域

（1)异染色质结构与功能动态中基因表达调控的高通量测序数据分析
（2）piRNA调控转座子的高通量测序数据分析

科研成果

主要科研成果（#共同第一作者, *通讯作者）如下：

1. Zhao, K.# , Cheng, S. # , Miao, N. # , Xu, P. # , Lu, X. # , Zhang, Y. # , Wang, M., Ouyang, X., Yuan, X., Liu, W., et al. (2019). A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation. Nat Cell Biol 21, 1261–1272.


2.Gu, J.# , Wang, M.# , Yang, Y., Qiu, D., Zhang, Y., Ma, J., Zhou, Y., Hannon, G.J., and Yu, Y. (2018). GoldCLIP: Gel-omitted Ligation-dependent CLIP. Genomics, Proteomics & Bioinformatics 16, 136–143.


3. Wang, M., Fleming, J., Li, Z., Li, C., Zhang, H., Xue, Y., Chen, M., Zhang, Z., Zhang, X.-E., and Bi, L. (2016). An automated approach for global identification of sRNA-encoding regions in RNA-Seq data from Mycobacterium tuberculosis. Acta Biochim Biophys Sin (Shanghai) 48, 544–553.

代表性论著：

1. Zhao K^#, Cheng S^#, Miao N^#, Xu P^#, Lu X^#, Zhang Y^#, Wang M, Ouyang X, Yuan X, Liu W, Lu X, Zhou P, Gu J, Zhang Y, Qiu D, Jin Z, Su C, Peng C, Wang JH, Dong MQ, Wan Y, Ma J, Cheng H, Huang Y, Yu Y. A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation. Nat Cell Biol. 2019 Oct;21(10):1261-1272. doi: 10.1038/s41556-019-0396-0.

2. 

3. Gu, J. ^# , Wang, M. ^#, Yang, Y., Qiu, D., Zhang, Y., Ma, J., Zhou, Y., Hannon, G.J., and Yu, Y*. (2018). GoldCLIP: Gel-omitted Ligation-dependent CLIP. Genomics, Proteomics & Bioinformatics. 16, 136–143. doi: 10.1016/j.gpb.2018.04.003.

4. Wang, M., Fleming, J., Li, Z., Li, C., Zhang, H., Xue, Y., Chen, M., Zhang, Z., Zhang, X.-E., and Bi, L.* (2016). An automated approach for global identification of sRNA-encoding regions in RNA-Seq data from Mycobacterium tuberculosis. Acta Biochim Biophys Sin (Shanghai). 48, 544–553. doi: 10.1093/abbs/gmw037