文豪

博士 研究主管

EMAIL：WENHAOPHD@OUTLOOK.COM

个人简介

文豪，医学博士，博士后。2020年于广州中医药大学获得医学博士学位，同年在中山大学从事博士后研究，顺利出站后加入广州市妇女儿童医疗中心优生围产研究所。 主持中国博士后科学基金面上项目1项，参与国家自然科学基金面上项目1项（第一参与人）、广东省课题多项，公开发表学术论文多篇， 目前为世界中医药学会联合会临床疗效评价委员会委员、生殖科学专业委员会委员。

研究领域

1)胎儿生长受限发病机制与诊治研究
2)机器学习算法在生殖领域的应用研究
3)临床研究及循证医学中的统计方法

科研成果

主要科研成果（#共同第一作者, *通讯作者）如下：

1. Wen H#, Xiang X #, Yong Jiang, Haoyu Zhang, Peiming Zhang, Rouhao Chen, Xiaojing Wei, Yu Dong, Songhua Xiao*, Liming Lu*. Comparative efficacy of psychosocial interventions for opioid-dependent people receiving methadone maintenance treatment: A network meta-analysis. Addiction.2023;118(6):1029-1039. doi:10.1111/add.16167.

2. Dong Y, Fan B, Yan E, Chen R, Wei X, Zhan J, Zeng J, Wen H*, Lu L*. Decision tree model based prediction of the efficacy of acupuncture in methadone maintenance treatment. Front Neurol.2022 Oct 6;13:956255. doi: 10.3389/fneur.2022.956255.

3. Lu L #, Zhang Y#, Ge S#,Wen H#, Tang X, Zeng JC, Wang L, Zeng Z, Rada G, Ávila C, Vergara C, Chen R, Dong Y, Wei X, Luo W, Wang L, Guyatt G, Tang CZ, Xu NG.*. Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies. BMJ Open.2022 Jun 6;12(6):e056803. doi: 10.1136/bmjopen-2021-056803.

4. Lu L , Zhang Y, Tang X, Ge S, Wen H, Zeng J, Wang L, Zeng Z, Rada G, Ávila C, Vergara C, Tang Y, Zhang P, Chen R, Dong Y, Wei X, Luo W, Wang L, Guyatt G, Tang C, Xu N*. Evidence on acupuncture therapies is underused in clinical practice and health policy. BMJ. 2022 Feb 25;376:e067475. doi: 10.1136/bmj-2021-067475.

5. Luo W , Wen H, Ge S, Tang C, Liu X, Lu L*. Development of a Sex-Specific Risk Scoring System for the Prediction of Cognitively Normal People to Patients With Mild Cognitive Impairment (SRSS-CNMCI). Front Aging Neurosci..2022 Jan 25;13:774804. doi: 10.3389/fnagi.2021.774804.

6. Wen H , Chen R, Zhang P, Wei X, Dong Y, Ge S, Luo W, Zhou Y, Xiao S, Lu L*.Acupuncture for Opioid Dependence Patients Receiving Methadone Maintenance Treatment: A Network Meta-Analysis. Front Psychiatry. Front Psychiatry. 2021 Dec 13;12:767613. doi: 10.3389/fpsyt.2021.767613.

7. Wen H, Wei X, Ge S, Zeng J, Luo W, Chen R, Dong Y, Xiao S, Lai Y, Lu L* . Clinical and Economic Evaluation of Acupuncture for Opioid-Dependent Patients Receiving Methadone Maintenance Treatment: The Integrative Clinical Trial and Evidence-Based Data. Front Public Health. 2021 Aug 16;9:689753. doi: 10.3389/fpubh.2021.689753.

8. Wen H , Xu S, Zeng J, Ge S, Liao Y, Tang C, Xiao S, Lu L*. Effect of acupuncture for methadone maintenance treatment patients: study protocol of a randomized clinical trial. Trials. 2020 Dec 7;21(1):1003. doi: 10.1186/s13063-020-04930-x.

9. Lu L #, Li F#, Wen H#, Ge S, Zeng J, Luo W, Wang L, Tang C, Xu N.*. An evidence mapping and analysis of registered COVID-19 clinical trials in China. BMC Med.2020 Jun 1;18(1):167. doi: 10.1186/s12916-020-01612-y.

10. Cai Y, Song Y, He M, He W, Zhong X, Wen H*, Wei Q*. Global prevalence and incidence of hallux valgus: a systematic review and meta-analysis. J Foot Ankle Res. 2023 Sep 20;16(1):63. doi: 10.1186/s13047-023-00661-9.


11. Lai X, Wen H, Li Y, Lu L, Tang C. The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis. Front Aging Neurosci. 2020 Jun 5;12:121. doi: 10.3389/fnagi.2020.00121.


12. Qiu X, Tan G, Wen H, Lian L, Xiao S. Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival. Ann Transl Med. 2021 Apr;9(8):692. doi: 10.21037/atm-21-1523.


13. Wen X, Li K, Wen H, Wang Q, Wu Z, Yao X, Jiao B, Sun P, Ge S, Wen C, Lu L. Acupuncture-Related Therapies for Parkinson's Disease: A Meta-Analysis and Qualitative Review. Front Aging Neurosci. 2021 Jul 1;13:676827. doi: 10.3389/fnagi.2021.676827.


14. Dai YK, Wu YB, Wen H, Li RL, Chen WJ, Tang C, Lu L, Hu L. Different Traditional Herbal Medicines for the Treatment of Gastroesophageal Reflux Disease in Adults. Front Pharmacol. 2020 Jul 16;11:884. doi: 10.3389/fphar.2020.00884.


15. Li C, Tang X, Zheng X, Ge S, Wen H, Lin X, Chen Z, Lu L. Global Prevalence and Incidence Estimates of Oral Lichen Planus: A Systematic Review and Meta-analysis. JAMA Dermatol. 2020 Feb 1;156(2):172-181. doi: 10.1001/jamadermatol.2019.3797.


16. Lu L, Zheng X, Wang S, Tang C, Zhang Y, Yao G, Zeng J, Ge S, Wen H, Xu M, Guyatt G, Xu N. Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2020 Dec;91(12):1316-1324. doi: 10.1136/jnnp-2020-323497.


17. Wang Q, Xiao X, Liang Y, Wen H, Wen X, Gu M, Ren C, Li K, Yu L, Lu L. Diagnostic Performance of Diffusion MRI for differentiating Benign and Malignant Nonfatty Musculoskeletal Soft Tissue Tumors: A Systematic Review and Meta-analysis. J Cancer. 2021 Oct 28;12(24):7399-7412. doi: 10.7150/jca.62131.


18. Wang Y, Yan X, Zhan J, Zhang P, Zhang G, Ge S, Wen H, Wang L, Xu N, Lu L. Neuroimaging Markers of Cerebral Small Vessel Disease on Hemorrhagic Transformation and Functional Outcome After Intravenous Thrombolysis in Patients With Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. Front Aging Neurosci. 2021 Jul 13;13:692942. doi: 10.3389/fnagi.2021.692942.


19. Zhang P, Zhan J, Wang S, Tang Y, Chen H, Wang Y, Wei X, Wen H, Pan T, Chen Z, Tang C, Xu N, Lu L. Psychological Interventions on Abstinence in Patients with Alcohol Use Disorder: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Neuropsychiatr Dis Treat. 2022 Aug 23;18:1815-1830. doi: 10.2147/NDT.S372300.


20. Tang C, Duan Y, Zhang Y, Zhang Y, Chen Z, Tang X, Zeng J, Riley D, Lee MS, Kim YS, Zhao H, Marrone G, Zhu X, Ge S, Wen H, Zhao W, Zheng X, Solos I, Chen Y, Guyatt G, Lu L, Xu N; RIGHT (Reporting Items for Practice Guidelines in Healthcare) for Acupuncture Working Group. RIGHT for acupuncture: An extension of the RIGHT statement for clinical practice guidelines on acupuncture. J Clin Epidemiol. 2021 Nov;139:330-339. doi: 10.1016/j.jclinepi.2021.05.021.

代表性论著：

1. Wen H^#, Xiang X^#, Yong Jiang, Haoyu Zhang, Peiming Zhang, Rouhao Chen, Xiaojing Wei, Yu Dong, Songhua Xiao*, Liming Lu*. Comparative efficacy of psychosocial interventions for opioid-dependent people receiving methadone maintenance treatment: A network meta-analysis. Addiction.2023;118(6):1029-1039. doi:10.1111/add.16167.

2. Dong Y, Fan B, Yan E, Chen R, Wei X, Zhan J, Zeng J, Wen H*, Lu L*. Decision tree model based prediction of the efficacy of acupuncture in methadone maintenance treatment. Front Neurol.2022 Oct 6;13:956255. doi: 10.3389/fneur.2022.956255.

3. Lu L^#, Zhang Y^#, Ge S^#,Wen H^#, Tang X, Zeng JC, Wang L, Zeng Z, Rada G, Ávila C, Vergara C, Chen R, Dong Y, Wei X, Luo W, Wang L, Guyatt G, Tang CZ, Xu NG.*. Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies. BMJ Open.2022 Jun 6;12(6):e056803. doi: 10.1136/bmjopen-2021-056803.

4. Lu L, Zhang Y, Tang X, Ge S, Wen H, Zeng J, Wang L, Zeng Z, Rada G, Ávila C, Vergara C, Tang Y, Zhang P, Chen R, Dong Y, Wei X, Luo W, Wang L, Guyatt G, Tang C, Xu N*. Evidence on acupuncture therapies is underused in clinical practice and health policy. BMJ. 2022 Feb 25;376:e067475. doi: 10.1136/bmj-2021-067475.

5. Luo W , Wen H, Ge S, Tang C, Liu X, Lu L*. Development of a Sex-Specific Risk Scoring System for the Prediction of Cognitively Normal People to Patients With Mild Cognitive Impairment (SRSS-CNMCI). Front Aging Neurosci.2022 Jan 25;13:774804. doi: 10.3389/fnagi.2021.774804.

6. Wen H , Chen R, Zhang P, Wei X, Dong Y, Ge S, Luo W, Zhou Y, Xiao S, Lu L*.Acupuncture for Opioid Dependence Patients Receiving Methadone Maintenance Treatment: A Network Meta-Analysis. Front Psychiatry. 2021 Dec 13;12:767613. doi: 10.3389/fpsyt.2021.767613.

7. Wen H, Wei X, Ge S, Zeng J, Luo W, Chen R, Dong Y, Xiao S, Lai Y, Lu L* . Clinical and Economic Evaluation of Acupuncture for Opioid-Dependent Patients Receiving Methadone Maintenance Treatment: The Integrative Clinical Trial and Evidence-Based Data. Front Public Health. 2021 Aug 16;9:689753. doi: 10.3389/fpubh.2021.689753.

8. Wen H, Xu S, Zeng J, Ge S, Liao Y, Tang C, Xiao S, Lu L*. Effect of acupuncture for methadone maintenance treatment patients: study protocol of a randomized clinical trial. Trials. 2020 Dec 7;21(1):1003. doi: 10.1186/s13063-020-04930-x.

9. Lu L^#, Li F^#, Wen H^#, Ge S, Zeng J, Luo W, Wang L, Tang C, Xu N.*. An evidence mapping and analysis of registered COVID-19 clinical trials in China. BMC Med.2020 Jun 1;18(1):167. doi: 10.1186/s12916-020-01612-y.

10. Cai Y, Song Y, He M, He W, Zhong X, Wen H*, Wei Q*. Global prevalence and incidence of hallux valgus: a systematic review and meta-analysis. J Foot Ankle Res. 2023 Sep 20;16(1):63. doi: 10.1186/s13047-023-00661-9.

11. Lai X, Wen H, Li Y, Lu L, Tang C. The Comparative Efficacy of Multiple Interventions for Mild Cognitive Impairment in Alzheimer's Disease: A Bayesian Network Meta-Analysis. Front Aging Neurosci. 2020 Jun 5;12:121. doi: 10.3389/fnagi.2020.00121.

12. Qiu X, Tan G, Wen H, Lian L, Xiao S. Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival. Ann Transl Med. 2021 Apr;9(8):692. doi: 10.21037/atm-21-1523.