祝杲阳

博士 研究主管

个人简介

祝杲阳，博士，副研究员。2015年于清华大学学获分子细胞生物学方向博士学位，同年在南方医科大学从事博士后研究。 主持国家自然科学基金委青年科学基金1项，中国博士后科学基金面上项目2项，累计发表SCI论文多篇。

研究领域

干细胞稳态维持与调控

科研成果

主要科研成果（#共同第一作者, *通讯作者）如下：

1. Lili Yu, Meng Wu, Gaoyang Zhu* and Yang Xu*. Emerging roles of the tumor suppressor p53 in metabolism. Frontiers in Cell and Developmental Biology. 2021,9:762742.

2. Gaoyang Zhu, Chaoyun Pan, Jin-Xin Bei, Bo Li, Chen Liang, Yang Xu*, Xuemei Fu*. Mutant p53 in Cancer Progression and Targeted Therapies. Frontiers in Oncology.2020,10:595187.

3. Gaoyang Zhu , Yue Ying, Kaiyuan Ji, Xinyue Duan, Taoyi Mai, Jinchul Kim, Qingjiao Li, Lili Yu*, Yang Xu*. p53 coordinates glucose and choline metabolism during the mesendoderm differentiation of human embryonic stem cells. Stem Cell Research.2020,49:102067.

4. Gaoyang Zhu , Teng Fei, Zhongwei Li, Xiaohua Yan, Ye-Guang Chen*. Activin regulates self-renewal and differentiation of trophoblast stem cells by down-regulating the X-chromosome gene Bcor. Journal of Biological Chemistry .2015,290: 22019-22029.

5. Pengfei Xu # , Gaoyang Zhu #, Yixia Wang, Jiawei Sun, Xingfeng Liu, Ye-Guang Chen, Anming Meng*. Maternal Eomesodermin regulates zygotic Nodal gene expression for mesendoderm induction in zebrafish embryos. Journal of Molecular Cell Biology.. 2014,6:272–285.

代表性论著：

1. Yu L, Wu M, Zhu G*, Xu Y*. Emerging Roles of the Tumor Suppressor p53 in Metabolism. Front Cell Dev Biol. 2022 Jan 18;9:762742. doi: 10.3389/fcell.2021.762742.

2. Zhu G, Pan C, Bei JX, Li B, Liang C, Xu Y*, Fu X*. Mutant p53 in Cancer Progression and Targeted Therapies. Front Oncol. 2020 Nov 6;10:595187. doi: 10.3389/fonc.2020.595187.

3. Zhu G, Ying Y, Ji K, Duan X, Mai T, Kim J, Li Q, Yu L*, Xu Y*. p53 coordinates glucose and choline metabolism during the mesendoderm differentiation of human embryonic stem cells. Stem Cell Res. 2020 Dec;49:102067. doi: 10.1016/j.scr.2020.102067.

4. Zhu G, Fei T, Li Z, Yan X, Chen YG*. Activin Regulates Self-renewal and Differentiation of Trophoblast Stem Cells by Down-regulating the X Chromosome Gene Bcor. J Biol Chem. 2015 Sep 4;290(36):22019-29. doi: 10.1074/jbc.M115.674127.

5. Xu P^#, Zhu G^#, Wang Y, Sun J, Liu X, Chen YG, Meng A*. Maternal Eomesodermin regulates zygotic nodal gene expression for mesendoderm induction in zebrafish embryos. J Mol Cell Biol. 2014 Aug;6(4):272-85. doi: 10.1093/jmcb/mju028.